Tonight’s (2/19/2009) presentation at the MaineTech Bioinformatics Special Interest Group meeting has been postponed due to weather. It has been rescheduled for March 19th.
Biological Signal Processing (BSP): Strategies for handling physical, chemical, and biological noise.
Peter Leopold, BioAnalyte Inc.
Biological data measured with modern analytical instruments (mass spec, NMR, UV) is a convolution of useful signal with three kinds of noise: biological, chemical and physical. In this presentation, we will describe how to approach the many degrees of variability in data to ascertain what’s noise and what’s signal. Successful data analysis boils down to the choices of intelligently chosen Bayesian priors coupled with replicate data sets. Several examples, including a mass spectrometry survey of differential protein expression in rat liver, will be discussed.
About the speaker.
Peter Leopold, Ph.D. is a 1985 graduate of Georgetown University and a 1992 graduate of UCSD, where he received a Ph.D. in physics. He was a post-doc in the Harvard Chemistry Dept, a software scientist at Bruker Daltonics, and vice president of ProteiGene Inc. before founding BioAnalyte in Portland in 2001. He has been a Portland resident since 2000. Leopold is on the steering committee of the BioSIG and Software Testing groups at TechMaine.
For more information, see http://www.techmaine.com/biosig-01-26-09